Association of Admission Serum Resistin Level with Acute ST-Segment Elevation Myocardial Infarction in Iraqi Patients

Iraqi Journal of Pharmaceutical Sciences

ARTICLE

Dheyaa J.Kadhim¹  Kassim J.Al-Shamma¹  Adeeb G. Hussein² 

[1] Department of Clinical Pharmacy, College of Pharmacy, University of Baghdad;Ministry of health, Al-Yarmouk Teaching Hospital

关键词: Resistin;    acute ST-segment elevation myocardial infarction;    adipokines.;   

DOI  :  10.31351/vol22iss1pp90-96

学科分类：计算机网络和通讯

来源: College of Pharmacy University of Baghdad

【 摘 要 】

Human resistin is an adipokine, with a possible link to coronary heart disease.A few studies were done about resistin in acute phase of ST-segment elevation myocardial infarction (STEMI) especially in Iraqi patients. Accordingly we design a study to investigate the association between resistin concentration and acute phase of STEMI in Iraqi patients. The present study was carried out at Al-Yarmouk Teaching Hospital from December 2011 until June 2012. Serum resistin levels were measured in 50 patients with acute STEMI (mean age: 58.16 ± 11.73 years) at the first 12 hours of admission and 34 normal controls (mean age: 53.98 ± 15.46 years) matched for age, sex and other risk factors. Resistin level in patients with acute STEMI (13.08 ng/mL) was significantly higher than that of the control group (5.31 ng/mL) (p < 0.0001). The study revealed a significant negative correlation between serum resistin level and serum adiponectin level among patients.

【 授权许可】

CC BY