Five-year prospective multi-center cohort study of patients with giant cell arteritis in Greece

Mediterranean Journal of Rheumatology

ARTICLE

Christina Tsalapaki¹  Eleni Nikitopoulou¹  Kyriaki A. Boki³  Dimitrios Boumpas¹  Petros P. Sfikakis¹  Georgios Vosvotekas⁶  Paraskevi V. Voulgari⁷  Dimitrios Vassilopoulos¹ 

[1] Joint Rheumatology Program, National and Kapodistrian University of Athens, School of Medicine;Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, Hippokration General Hospital;Rheumatology Unit, Sismanoglio Hospital;4th Department of Medicine, Attikon Hospital, National and Kapodistrian University of Athens, School of Medicine;First Department of Propedeutic Internal Medicine, National and Kapodistrian University of Athens School of Medicine;Private practice;Rheumatology Clinic, University of Ioannina

关键词: Giant cell arteritis;    glucocorticoids;    relapses;    comorbidities;    methotrexate;    osteoporosis;   

DOI  :  10.31138/mjr.29.2.103

学科分类：社会科学、人文和艺术（综合）

来源: PCO Convin S.A.

【 摘 要 】

Giant cell arteritis (GCA) is the most common systemic vasculitis in the aged population associated with significant morbidity due to the long term administration of corticosteroids and the presence of various comorbidities. Data regarding its current treatment modalities, comorbidities, morbidity and mortality in Greece are limited. In this multi-center, prospective study that begun at the end of 2015 patients with newly diagnosed GCA according to the modified 1990 ACR criteria, as well as individuals with established or relapsing disease have been included. During the 1st phase of the study that is still ongoing, data are being collected concerning demographic and clinical characteristics of the patients, treatment at the onset of the disease and at relapses, relapses, adverse events of therapy, comorbidities, hospitalizations and deaths. During the 2nd and 3rd phase of the study patients will be reevaluated 2 and 5 years after their 1st evaluation. The study is expected to provide valuable data regarding the current clinical characteristics, co-morbidities, therapeutic regimens used, relapse rate, morbidity and mortality of patients with GCA.

【 授权许可】

CC BY-NC