Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome

Tuberculosis and Respiratory Diseases

article

Seung Hyun Lee¹  Jae Hyung Kim¹  Sejin Park¹  Chang Youn Won¹  Joo-Hyun Lee¹  Seong Yoon Yi¹  Hye Kyeong Park¹  Sun Hee Chang²  Hoon Jung¹  Sung-Soon Lee¹  Hyeon-Kyoung Koo¹ 

[1] Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine;Department of Pathology, Inje University Ilsan Paik Hospital, Inje University College of Medicine

关键词: Myelodysplastic Syndromes;    Vasculitis;    Leukocytoclastic;    Cutaneous;    Paraneoplastic Syndromes;    Pneumonia;   

DOI  :  10.4046/trd.2016.79.4.302

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS.

【 授权许可】

CC BY-NC