Rare Association of Leukocytoclastic Vasculitis in Visceral Leishmaniaisis

Oman Medical Journal

Sweta Rajpal2,¹  Kirti Gupta3 and²  Ram V. Nampoothiri1,³  Sanjay Jain³  Bharath A. Chhabria1*,³ 

[1] Department of Hematopathology, Postgraduate Institute of Medical Education and Research,Chandigarh, India;Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India;Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India;

关键词: Leishmaniasis;    Visceral;    Vasculitis;    Leukocytoclastic;    Cutaneous;   

DOI  :  10.5001/omj.2019.11

来源: DOAJ

【 摘 要 】

A 30-year-old man presented with fever, hepatosplenomegaly, and a rash over his lower limbs (palpable purpura). Evaluation revealed pancytopenia and hypergammaglobulinemia. A subsequent bone marrow examination and serology confirmed visceral leishmaniasis (kala-azar), while the biopsy of skin lesion suggested leukocytoclastic vasculitis. No alternate cause of vasculitis was forthcoming, and the patient was treated with conventional amphotericin B for 14 days after which resolution of symptoms (including the rash) was noted. Cutaneous vasculitis is an extremely rare complication following visceral leishmaniasis with no known cases reported thus far. Hence, a high index of suspicion is warranted in achieving timely diagnosis and initiation of appropriate therapy.

【 授权许可】

Unknown