Tuberculosis Infection and Latent Tuberculosis

Tuberculosis and Respiratory Diseases

article

Seung Heon Lee¹ 

[1] Division of Pulmonary, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine

关键词: Tuberculosis;    Infection;    Transmission;    Infection Control;    Latent Tuberculosis;   

DOI  :  10.4046/trd.2016.79.4.201

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Active tuberculosis (TB) has a greater burden of TB bacilli than latent TB and acts as an infection source for contacts. Latent tuberculosis infection (LTBI) is the state in which humans are infected with Mycobacterium tuberculosis without any clinical symptoms, radiological abnormality, or microbiological evidence. TB is transmissible by respiratory droplet nucleus of 1-5 µm in diameter, containing 1-10 TB bacilli. TB transmission is affected by the strength of the infectious source, infectiousness of TB bacilli, immunoresistance of the host, environmental stresses, and biosocial factors. Infection controls to reduce TB transmission consist of managerial activities, administrative control, engineering control, environmental control, and personal protective equipment provision. However, diagnosis and treatment for LTBI as a national TB control program is an important strategy on the precondition that active TB is not missed. Therefore, more concrete evidences for LTBI management based on clinical and public perspectives are needed.

【 授权许可】

CC BY-NC