Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR -Mutant Lung Cancer

Tuberculosis and Respiratory Diseases

article

Mihong Choi¹  Youngjoo Lee¹  Sang Hyun Hwang²  Jin Soo Lee¹ 

[1] Department of Internal Medicine, Center for Diagnostic Oncology, National Cancer Center;Department of Laboratory Medicine, Center for Diagnostic Oncology, National Cancer Center

关键词: EGFR Tyrosine Kinase Inhibitor 324674;    Nocardia Infections;    Carcinoma;    Non-Small-Cell Lung;    Radiosurgery;   

DOI  :  10.4046/trd.2014.77.6.271

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Disease flare-up after discontinuing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been considered as a critical issue in lung cancer patients who have experienced radiologic progression after showing initial durable response. This is a case of systemic nocardiosis that occurred after chronic steroid use for radionecrosis from stereotactic radiosurgery. It was initially thought as a disease flare-up after stopping EGFR-TKI.

【 授权许可】

CC BY-NC