A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy

Tuberculosis and Respiratory Diseases

article

Yoon Jeong Lee¹  Jun-Hyun Kim¹  Sun Woong Kim¹  Won Chan Kang¹  Soo Jung Kim¹  Ji Hye Kim¹  Sun Jong Kim¹ 

[1] Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine

关键词: Irinotecan;    IFL Protocol;    Cryptogenic Organizing Pneumonia;    Colorectal Neoplasmsoxaliplatin;   

DOI  :  10.4046/trd.2014.77.6.262

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiolitis obliterans organizing pneumonia) associated with FOLFIRI chemotherapy has been reported. We experienced a case of a 62-year-old man who presented persistent dry cough and progressive dyspnea after receiving chemotherapy with FOLFIRI regimen. After surgical lung biopsy, the patient was diagnosed with FOLFIRI chemotherapy-induced organizing pneumonia which was successfully treated with steroid therapy.

【 授权许可】

CC BY-NC