The Effects of Bronchiectasis on Asthma Exacerbation

Tuberculosis and Respiratory Diseases

article

Hye Ran Kang¹  Gyu-Sik Choi¹  Sun Jin Park¹  Yoon Kyung Song¹  Jeong Min Kim¹  Junghoon Ha¹  Yung Hee Lee¹  Byoung Hoon Lee¹  Sang-Hoon Kim¹  Jae Hyung Lee¹ 

[1] Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine

关键词: Bronchiectasis;    Asthma;    Disease Exacerbation;   

DOI  :  10.4046/trd.2014.77.5.209

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

Background Bronchiectasis and asthma are different in many respects, but some patients have both conditions. Studies assessing the effect of bronchiectasis on asthma exacerbation are rare. The aim of this study is to investigate the effect of bronchiectasis on asthma exacerbation. Methods We enrolled 2,270 asthma patients who were followed up in our hospital. Fifty patients had bronchiectasis and asthma. We selected fifty age- and sex-matched controls from the 2,220 asthma patients without bronchiectasis, and assessed asthma exacerbation and its severity based on the annual incidence of total asthma exacerbation, annual prevalence of steroid use, and frequency of emergency room visits and hospitalizations due to asthma exacerbation in each group. Results Fifty patients (2.2%) had bronchiectasis and asthma. The annual incidence of asthma exacerbation was higher in patients with asthma and bronchiectasis than in patients with asthma alone (1.08±1.68 vs. 0.35±0.42, p=0.004). The annual prevalence of steroid use (0.9±1.54 vs. 0.26±0.36, p=0.006) and the frequency of emergency room visits (0.46±0.84 vs. 0.02±0.13, p=0.001) due to asthma exacerbation were also higher in patients with asthma and bronchiectasis than in patients with asthma alone. Conclusion Bronchiectasis is associated with difficult asthma control.

【 授权许可】

CC BY-NC