Lung Cancer Screening: Subsequent Evidences of National Lung Screening Trial

Tuberculosis and Respiratory Diseases

article

Young Sik Park¹ 

[1] Department of Internal Medicine, Seoul National University Hospital

关键词: Lung Neoplasms;    Early Detection of Cancer;    Tomography;    X-Ray Computed;    Thorax;   

DOI  :  10.4046/trd.2014.77.2.55

学科分类：医学（综合）

来源: The Korean Academy of Tuberculosis and Respiratory Diseases

【 摘 要 】

The US National Lung Screening Trial (NLST) demonstrated a 20% reduction in lung cancer mortality and a 6.7% decrease in all-cause mortality. The NLST is the only trial showing positive results in a high-risk population, such as in patients with old age and heavy ever smokers. Lung cancer screening using a low-dose chest computed tomography might be beneficial for the high-risk group. However, there may also be potential adverse outcomes in terms of over diagnosis, bias and cost-effectiveness. Until now, lung cancer screening remains controversial. In this review, we wish to discuss the evolution of lung cancer screening and summarize existing evidences and recommendations.

【 授权许可】

CC BY-NC