Tuberculosis and Respiratory Diseases | |
Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate | |
article | |
Jin Sun Park1  Eul Sik Jung1  Woosuk Choi1  Soo Yong Park1  Min Young Rim1  Inku Yu1  Hyeonsu Park1  Sang Min Lee1  Jeong-Woong Park1  Sung Hwan Jeong1  Sang Pyo Lee1  Sanghui Park2  | |
[1] Department of Internal Medicine, Gachon University Gil Hospital, Gachon University Medicine and Science, Incheon;Department of Pathology, Ewha Womans University School of Medicine | |
关键词: Nontuberculous Mycobacteria; Tuberculosis; Pulmonary; Methotrexate; Arthiritis; Rheumatoid; Bronchial Diseases; | |
DOI : 10.4046/trd.2013.75.1.28 | |
学科分类:医学(综合) | |
来源: The Korean Academy of Tuberculosis and Respiratory Diseases | |
【 摘 要 】
Methotrexate (MTX) has been established as a standard disease-modifying anti-rheumatic drug. If adequate disease control is achieved for a reasonable period of time, tapering the MTX dosage is recommended because the chronic use of MTX can result in opportunistic infection. We present here a case of a woman with rheumatoid arthritis taking MTX, and the woman developed actively caseating endobronchial Mycobacterium intracellulare disease with pulmonary infiltrations. After discontinuing the MTX, the patient was able to tolerate 18 months of antimycobacterial treatment without flare ups of rheumatoid arthritis, and she completely recovered from nontuberculous mycobacterial respiratory disease.
【 授权许可】
CC BY-NC
【 预 览 】
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