The burden and predisposing factors of non-communicable diseases in Mashhad University of Medical Sciences personnel: a prospective 15-year organizational cohort study protocol and baseline assessment

BMC Public Health

Mohammad Tayebi¹  Ali Khorsand²  Ameen Abu-Hanna³  Fariba Tohidinezhad⁴  Saeid Eslami⁵  Reza Rezvani⁶  Lahya Afshari Saleh⁷  Ali Moradi⁸  Donya Farrokh⁹  Bita Abbasi⁹  Masoud Pezeshki Rad⁹  Mahmoud Tavakoli^1,10  Siamak Zarei-Ghanavati^1,11  Majid Abrishami^1,11  Mitra Ahadi^1,12  Hossein Poustchi^1,13  Mahnaz Amini^1,14  Seyed Rasoul Zakavi^1,15 

[1] Atherosclerosis Prevention Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Complementary and Chinese Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Medical Informatics, Amsterdam UMC-Location AMC, University of Amsterdam, Amsterdam, The Netherlands;Department of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Medical Informatics, Amsterdam UMC-Location AMC, University of Amsterdam, Amsterdam, The Netherlands;Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Occupational Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Orthopedic Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Urology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Gastroenterology and Hepatology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran;Lung and Tuberculosis Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran;Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;

关键词: Non-communicable diseases;    Outcome assessment;    Etiology;    Cohort studies;    Developing countries;   

DOI  :  10.1186/s12889-020-09704-3

来源: Springer

【 摘 要 】

BackgroundThe rising burden of premature mortality for Non-Communicable Diseases (NCDs) in developing countries necessitates the institutionalization of a comprehensive surveillance framework to track trends and provide evidence to design, implement, and evaluate preventive strategies. This study aims to conduct an organization-based prospective cohort study on the NCDs and NCD-related secondary outcomes in adult personnel of the Mashhad University of Medical Sciences (MUMS) as main target population.MethodsThis study was designed to recruit 12,000 adults aged between 30 and 70 years for 15 years. Baseline assessment includes a wide range of established NCD risk factors obtaining by face-to-face interview or examination. The questionnaires consist of demographic and socioeconomic characteristics, lifestyle pattern, fuel consumption and pesticide exposures, occupational history and hazards, personal and familial medical history, medication profile, oral hygiene, reproduction history, dietary intake, and psychological conditions. Examinations include body size and composition test, abdominopelvic and thyroid ultrasonography, orthopedic evaluation, pulse wave velocity test, electrocardiography, blood pressure measurement, smell-taste evaluation, spirometry, mammography, and preferred tea temperature assessment. Routine biochemical, cell count, and fecal occult blood tests are also performed, and the biological samples (i.e., blood, urine, hair, and nail) are stored in preserving temperature. Annual telephone interviews and repeated examinations at 5-year intervals are planned to update information on health status and its determinants.ResultsA total of 5287 individuals (mean age of 43.9 ± 7.6 and 45.9% male) were included in the study thus far. About 18.5% were nurses and midwives and 44.2% had at least bachelor’s degree. Fatty liver (15.4%), thyroid disorders (11.2%), hypertension (8.8%), and diabetes (4.9%) were the most prevalent NCDs. A large proportion of the population had some degree of anxiety (64.2%). Low physical activity (13 ± 22.4 min per day), high calorie intake (3079 ± 1252), and poor pulse-wave velocity (7.2 ± 1.6 m/s) highlight the need for strategies to improve lifestyle behaviors.ConclusionThe PERSIAN Organizational Cohort study in Mashhad University of Medical Sciences is the first organizational cohort study in a metropolitan city of Iran aiming to provide a large data repository on the prevalence and risk factors of the NCDs in a developing country for future national and international research cooperation.

【 授权许可】

CC BY