Successful treatment of pyopneumothorax secondary to Streptococcus constellatus infection with linezolid: a case report and review of the literature

Journal of Medical Case Reports

Zhaorui Zhang¹  Binbin Xiao¹  Zhixin Liang¹ 

[1] Department of Respiratory Medicine, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, 100853, Beijing City, People’s Republic of China;

关键词: Pyopneumothorax;    Streptococcus constellatus;    linezolid;    case report;    Streptococcus milleri;    treatment;   

DOI  :  10.1186/s13256-020-02475-w

来源: Springer

【 摘 要 】

BackgroundPyopneumothorax secondary to Streptococcus constellatus infection is a clinically rare event, and few cases have been reported.Case presentationWe report the case of a 55-year-old Han Chinese man with underlying diabetes who presented with fever of 17 days duration. A pulmonary computed tomography scan revealed right-sided massive pyopneumothorax. A culture of the pleural effusion and blood grew S. constellatus. A drug sensitivity test showed that the isolate was sensitive to linezolid, penicillin G, cefotaxime, vancomycin, and cefuroxime. Our patient was treated with linezolid for a total of 6 weeks. Subsequently, his chest computed tomography scan showed improved lung condition.ConclusionTo the best of our knowledge, this is the first case of pyopneumothorax secondary to S. constellatus to be treated with linezolid. Pyopneumothorax may be caused by streptococcal infection, and linezolid is another good choice for treatment.

【 授权许可】

CC BY