Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light

Nano-Micro Letters

Tianqi Zhang¹  Jianhua Liu¹  Longhai Jin¹  Shuyan Song²  Xiaoqing Li²  Na Yin²  Ying Zhao²  Rui Niu²  Yang Liu²  Yinghui Wang²  Dongzhi Xue²  Songtao Zhang³  Hongjie Zhang⁴ 

[1] Department of Radiology, The Second Hospital of Jilin University, 130041, Changchun, People’s Republic of China;State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), 130022, Changchun, People’s Republic of China;State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), 130022, Changchun, People’s Republic of China;University of Chinese Academy of Sciences, 100049, Beijing, People’s Republic of China;State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), 130022, Changchun, People’s Republic of China;University of Chinese Academy of Sciences, 100049, Beijing, People’s Republic of China;Department of Chemistry, Tsinghua University, 100084, Beijing, People’s Republic of China;

关键词: Chemodynamic therapy;    Fenton;    Co-catalysis;    Photothermal effect;    NIR;   

DOI  :  10.1007/s40820-020-00516-z

来源: Springer

【 摘 要 】

tsThe MoS2 nanosheets served as co-catalyst could reduce Fe3+ ions with lower Fenton reaction activity into the highly reactive Fe2+ ions, thereby boosting the production of hydroxyl radical (•OH) for high efficiency chemodynamic therapy (CDT).The photothermal effect of MoS2 nanosheets motivated by second near-infrared light could further improve the treatment effectiveness by synergetic photothermal-enhanced CDT and photothermal therapy.

【 授权许可】

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