Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

BMC Infectious Diseases

Flavia Moreno Alves de Souza¹  Gerson Fernando Mendes Pereira¹  Luisa Lina Villa²  Eliana Márcia Wendland³  Juliana Comerlato³  Bruna Vieira Fernandes³  Marina Bessel⁴  Natália Luiza Kops⁴  Jaqueline Driemeyer Horvath⁴ 

[1] Department of Chronic Conditions and Sexually Transmitted Infections, Ministry of Health, Brasília, Brazil;Faculdade de Medicina, University of São Paulo and Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil;Hospital Moinhos de Vento, PROADI – SUS, Ramiro Barcelos, 910, 90035-004, Porto Alegre, RS, Brazil;Federal University of Health Sciences of Porto Alegre, Graduate Programs in Health Sciences and Pediatrics, Porto Alegre, Brazil;Hospital Moinhos de Vento, Porto Alegre, Brazil;

关键词: Human papillomavirus;    Genital warts;    HPV;    Epidemiology;    Prevalence in young adults;   

DOI  :  10.1186/s12879-020-05376-x

来源: Springer

【 摘 要 】

BackgroundExternal genital lesions (EGL) are the most common sexually transmitted infections (STIs). We aimed to evaluate the prevalence, determinants and sex differences in EGL among young adults from Brazil.MethodsOverall, 7694 participants (aged 16 to 25 years) underwent an interview, genital examination and sampling for HPV genotyping.ResultsThe prevalence of EGL was 4.08% (234) and is more frequent in men (5.72%) than women (2.31%) (p <  0.001). Genital lesions were significantly associated with male sex, infection by high-risk and multiple HPV types, having more than two sexual partners in the last year, smoking status and the presence of other STI. While alcohol use was associated with a higher prevalence of EGL in women, same-sex sexual relationship increase the prevalence in men. In the EGL group, 67.79% (p = 0.032) were positive for HPV infection and the types HPV6 and HPV11 were the most prevalent ones.ConclusionThe prevalence of EGL in young adults was consistently high, and most cases were associated with genital HPV infection and STIs. Although men have a higher prevalence, both sexes share most genital lesion determinants. The promotion of sexual education and vaccination especially focus in young men, who are usually outside the targets of primary health care programmes, can prevent EGL in Brazilian young adults.

【 授权许可】

CC BY