Functional outcomes after combined iris and intraocular lens implantation in various iris and lens defects

BMC Ophthalmology

Ramin Khoramnia¹  Christian S. Mayer²  Andrea M. Hoffmann³  Lukas Reznicek³  Phillipp Prahs⁴ 

[1] Department of Ophthalmology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany;Department of Ophthalmology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany;Department of Ophthalmology, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany;Department of Ophthalmology, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany;Department of Ophthalmology, University of Regensburg, Regensburg, Germany;

关键词: Aniridia;    Pupillary reconstruction;    Ocular trauma;    Eye injury;    IOL;   

DOI  :  10.1186/s12886-020-01621-8

来源: Springer

【 摘 要 】

BackgroundTo assess the functional outcomes after combined iris and intraocular lens (IOL) repair in aniridia patients.MethodsRetrospective observational study in 59 aniridic and aphakic eyes for ArtificialIris (AI) and IOL reconstruction. The iris prostheses were placed together with the IOL in the capsular bag using an injection system or were fixed by transscleral suturing of the IOL and AI. The primary outcomes measured were visual acuity, contrast and glare sensitivity (Pelli-Robson chart for photopic and dark adaptometer for mesopic conditions), intraocular pressure, endothelial cell density (ECD) and patient impairment.ResultsBlunt trauma (37 eyes) and penetrating injuries (16 eyes) were observed more frequently than congenital aniridia (1 eye), iatrogenic causes (1 eye), aniridic state after severe iritis (2 eyes) or iris tumor (2 eyes). Monocular CDVA improved significantly (p < 0.0001) from median 0.7 logMAR (0.0–1.98) to 0.3 logMAR (− 0.08–2.0). Median pupillary area could significantly (p < 0.0001) be reduced by 79.3% from 51.27 mm2 (17.91 to 98.23) to 8.81 mm2 (4.16 to 8.84). Median ECD decreased from 2646.0 mm2 to 2497.5 mm2 (p = 0.007). Contrast and glare sensitivity improved significantly (p = 0.008) in photopic light conditions from 0.9 (0.0–1.95) to 1.35 (0.0–1.8). Patients reported to be highly satisfied with the functional improvement.ConclusionThe flexible ArtificialIris seems to be a safe and effective iris prosthesis in combination with an IOL having functionally and cosmetically exceptional reconstruction options.

【 授权许可】

CC BY