Effects of fumonisin B1 on selected biological responses and performance of broiler chickens

Pesquisa Veterinária Brasileira

Ricardo H. Rauber²  Maurício S. Oliveira¹  Adriano O. Mallmann¹  Paulo Dilkin¹  Carlos A. Mallmann¹  Leandro Z. Giacomini¹  Vladimir P. Nascimento² 

[1] ,Universidade Federal do Rio Grande do Sul Faculdade de Veterinária Centro de Diagnóstico e Pesquisa em Patologias AviáriasPorto Alegre RS ,Brazil

关键词: Fumonisin;    broiler;    performance;    intestinal morphology;    Fumonisina;    frango de corte;    desempenho;    morfologia intestinal;   

DOI  :  10.1590/S0100-736X2013000900006

来源: SciELO

【 摘 要 】

The objective of this study was to determine the effects of three doses of fumonisin B1 (0, 100, and 200mg/kg of feed) on biological variables (relative weight of liver [RWL], total plasma protein [TPP], albumin [Alb], calcium [Ca], phosphorus [P], uric acid [UA], alanine aminotransferase [ALT], aspartate aminotransferase [AST], gamma glutamyltransferase [GGT], alkaline phosphatase [AP], total cholesterol [Chol], triglycerides [Tri], sphinganine-to-sphingosine ratio [SA:SO], and C-reactive protein [CRP]), morphological evaluation of the small intestine (villus height [VH], crypt depth [CD], and villus-to-crypt ratio [V:C]), histological evaluation, and on performance (body weight [BW], feed intake [FI], and feed conversion rate [FCR]) of broiler chickens. Significant effects of FB were observed on BW and FI (reduced), on RWL, TPP, Ca, ALT, AST, GGT, Chol, and Tri (increased) at both 14 and 28 days evaluations. In addition, significant increase was observed on FCR, Alb, P, SA:SO, and CRP and significant reduction in UA, VH, and V:C only at the 28 days evaluation. Significant histological lesions were observed on liver and kidney of FB inoculated broilers at 14 and 28 days. Those results show that FB has a significant effect on biological and histological variables and on performance of broiler chickens.

【 授权许可】

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