Genetic characterization of Brazilian bovine viral diarrhea virus isolates by partial nucleotide sequencing of the 5'-UTR region

Pesquisa Veterinária Brasileira

Adriana Cortez²  Marcos B Heinemann¹  Alessandra Marnie M.g. De Castro²  Rodrigo M Soares²  Ana Maria V. Pinto¹  Amauri A. Alfieri¹  Eduardo F. Flores¹  Rômulo Cerqueira Leite¹  Leonardo J. Richtzenhain² 

[1] ,Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia São Paulo SP ,Brazil

关键词: BVDV-1;    BVDV-2;    Pestivirus;    phylogenetic analysis;    BVDV-1;    BVDV-2;    Pestivirus;    Brazil;    análise filogenética;   

DOI  :  10.1590/S0100-736X2006000400005

来源: SciELO

【 摘 要 】

Nineteen isolates of bovine viral diarrhea virus (BVDV) from Brazil were genetically characterized through partial nucleotide sequencing and analysis of the 5'UTR region. The isolates were grouped as BVDV-1 (11/19), BVDV-2 (6/19) or "atypical" pestivirus (2/19). Among the BVDV-1, eight isolates were classified as subgenotype BVDV-1a, whereas most (4 out of 6) BVDV-2 belonged to subgenotype 2b. Two isolates from aborted fetuses were not classified into any genetic group, being considered atypical BVDVs. Genetic diversity among Brazilian BVDV isolates may be responsible for vaccination and diag-nostic failure and therefore may influence the control strategies for BVDV infection in the country.

【 授权许可】

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