Genetic characterization of Brazilian bovine viral diarrhea virus isolates by partial nucleotide sequencing of the 5'-UTR region

Pesquisa Veterinária Brasileira

Cortez, Adriana⁵  Heinemann, Marcos B¹  Pinto, Ana Maria V.³  Castro, Alessandra Marnie M.G. de⁵  Richtzenhain, Leonardo J.⁵  Soares, Rodrigo M⁵  Flores, Eduardo F.⁴  Alfieri, Amauri A.²  Leite, Rômulo Cerqueira¹ 

[1] Universidade Federal de Minas Gerais, Belo Horizonte;Universidade Estadual de Londrina, Londrina;Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes;Universidade Federal de Santa Maria, Santa Maria;Universidade de São Paulo, São Paulo, Brazil

关键词: BVDV-1;    BVDV-2;    Pestivirus;    phylogenetic analysis.;   

DOI  :  10.1590/S0100-736X2006000400005

来源: Colegio Brasileiro de Patologia Animal-CBPA

【 摘 要 】

Nineteen isolates of bovine viral diarrhea virus (BVDV) from Brazil were genetically characterized through partial nucleotide sequencing and analysis of the 5'UTR region. The isolates were grouped as BVDV-1 (11/19), BVDV-2 (6/19) or "atypical" pestivirus (2/19). Among the BVDV-1, eight isolates were classified as subgenotype BVDV-1a, whereas most (4 out of 6) BVDV-2 belonged to subgenotype 2b. Two isolates from aborted fetuses were not classified into any genetic group, being considered atypical BVDVs. Genetic diversity among Brazilian BVDV isolates may be responsible for vaccination and diag-nostic failure and therefore may influence the control strategies for BVDV infection in the country. Index

【 授权许可】

CC BY-NC