Estudo fitoquímico e avaliação da atividade anti-inflamatória de Aeschynomene fluminensis vell. (Fabaceae)

Química Nova

Marlene Capelin Ignoato²  Rodrigo Monteiro Fabrão²  Ivânia Teresinha Albrecht Schuquel²  Marcos Felipe Pinatto Botelho²  Silvana Maria De Oliveira Santin²  Laura Lícia Milani De Arruda¹  Ciomar Aparecida Bersani-amado¹  Maria Conceição De Souza¹ 

[1] ,Universidade Estadual de Maringá Departamento de Química Maringá PR ,Brasil

关键词: Aeschynomene fluminensis;    flavonoides;    anti-inflammatory activity;   

DOI  :  10.1590/S0100-40422012001100028

来源: SciELO

【 摘 要 】

Phytochemical investigation of Aeschynomene fluminensis leaves and branches led to isolation of the flavonoid glycosides kaempferol 3,7-di-O-α-L-rhamnopyranoside, kaempferol 7-O-α-L-rhamnopyranoside, kaempferol 3-O-apiofuranosil-7-O- rhamnopyranoside, quercitin 3-O-α-L-rhamnopyranoside, quercitin 3-O-arabinofuranoside, 8-β-D-glucopyranosyl 4',5,7-trihydroxyflavanone, the isoflavonoid 4',7-di-hydroxy-isoflavone, the dimer epicatechin-(2β→7, 4β→8)- epicatechin, the polyol 3-O-methyl-chiro-inositol and two steroids in sitosterol and stigmasterol mixture. These compounds were identified by NMR ¹H and 13C and compared with literature data. Anti-inflammatory activity of the crude methanolic extract and its fractions was evaluated.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License