Phytochemical study and evaluation of anti-inflammatory activity of Aeschynomene fluminensis vell. (Fabaceae)

Quimica nova

Bersani-Amado, Ciomar Aparecida¹  Fabrão, Rodrigo Monteiro¹  Santin, Silvana Maria de Oliveira¹  Botelho, Marcos Felipe Pinatto¹  Arruda, Laura Lícia Milani de¹  Ignoato, Marlene Capelin¹  Souza, Maria Conceição de¹  Schuquel, Ivânia Teresinha Albrecht¹ 

[1] Universidade Estadual de Maringá, Maringá, Brasil

关键词: Aeschynomene fluminensis;    flavonoides;    anti-inflammatory activity.;   

DOI  :  10.1590/S0100-40422012001100028

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Phytochemical investigation of Aeschynomene fluminensis leaves and branches led to isolation of the flavonoid glycosides kaempferol 3,7-di-O-α-L-rhamnopyranoside, kaempferol 7-O-α-L-rhamnopyranoside, kaempferol 3-O-apiofuranosil-7-O- rhamnopyranoside, quercitin 3-O-α-L-rhamnopyranoside, quercitin 3-O-arabinofuranoside, 8-β-D-glucopyranosyl 4',5,7-trihydroxyflavanone, the isoflavonoid 4',7-di-hydroxy-isoflavone, the dimer epicatechin-(2β→7, 4β→8)- epicatechin, the polyol 3-O-methyl-chiro-inositol and two steroids in sitosterol and stigmasterol mixture. These compounds were identified by NMR 1H and 13C and compared with literature data. Anti-inflammatory activity of the crude methanolic extract and its fractions was evaluated.

【 授权许可】

CC BY