Aporphine alkaloids from Ocotea macrophylla (Lauraceae)

Química Nova

Ludy Cristina Pabon¹  Luis Enrique Cuca¹ 

[1] ,Universidad Nacional de Bogotá Departamento de Química, Facultad de Ciencias ,Colombia

关键词: Ocotea macrophylla;    aporphine alkaloids;    Lauraceae;   

DOI  :  10.1590/S0100-40422010000400021

来源: SciELO

【 摘 要 】

Four aporphine alkaloids from the wood of Ocotea macrophylla (Lauraceae) were isolated and characterized as (S)-3-methoxy-nordomesticine (1), (S)-N-ethoxycarbonyl-3-methoxy-nordomesticine (2), (S)-N-formyl-3-methoxy-nordomesticine (3) and (S)-N-methoxycarbonyl-3-methoxy-nordomesticine (4); alkaloids 2-4 are being report for the first time. The structure the isolated compounds were determined based on their spectral data and by comparison of their spectral data with values described in literature. The alkaloid fraction and compound 1 showed antifungal activity against Fusarium oxysporum f. sp. lycopersici and also compound 1 showed antimicrobial activity towards Staphylococcus aureus, Enterococcus faecalis as well.

【 授权许可】

CC BY-NC   
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