Aporphine alkaloids from Ocotea macrophylla (Lauraceae)

Química Nova

Universidad Nacional de Bogotá, Colombia¹  Pabon, Ludy Cristina¹  Cuca, Luis Enrique¹ 

关键词: Ocotea macrophylla;    aporphine alkaloids;    Lauraceae.;   

DOI  :  10.1590/S0100-40422010000400021

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Four aporphine alkaloids from the wood of Ocotea macrophylla (Lauraceae) were isolated and characterized as (S)-3-methoxy-nordomesticine (1), (S)-N-ethoxycarbonyl-3-methoxy-nordomesticine (2), (S)-N-formyl-3-methoxy-nordomesticine (3) and (S)-N-methoxycarbonyl-3-methoxy-nordomesticine (4); alkaloids 2-4 are being report for the first time. The structure the isolated compounds were determined based on their spectral data and by comparison of their spectral data with values described in literature. The alkaloid fraction and compound 1 showed antifungal activity against Fusarium oxysporum f. sp. lycopersici and also compound 1 showed antimicrobial activity towards Staphylococcus aureus, Enterococcus faecalis as well.

【 授权许可】

Unknown