Estudo fitoquímico da madeira de Guarea macrophylla (Meliaceae)

Química Nova

João Henrique G. Lago²  Nídia F. Roque¹ 

[1] ,Universidade Federal de São Paulo Departamento de Ciências Exatas e da Terra Diadema SP ,Brasil

关键词: Meliaceae;    Guarea macrophylla;    cycloartane triterpenoids;   

DOI  :  10.1590/S0100-40422009000900022

来源: SciELO

【 摘 要 】

In the present work, the crude ethanol extract from wood of G. macrophylla was submitted to liquid/liquid partition between hexane, CH2Cl2, EtOAc and n-BuOH. Each phase was individually chromatographed over silica gel, Sephadex LH-20 or Amberlite XAD-2 to give eight terpene derivatives, such as five sesquiterpenoids (caryophyllene oxide, guai-6-en-10β-ol, spathulenol, aromadendrane-4β,10α-diol and aloaromadendrane-4α,10β-diol) as well as three triterpenoids (cicloart-24-ene-3β,23(R*)-diol, cicloart-24-ene-3β,23(S*)-diol, and cicloart-23E-ene-3β,25-diol). Additionally, were isolated three fatty acids (linolenic, linoleic and stearic), two steroids (sitosterol and stigmasterol) and sacarose. The structures of all these compounds were characterized by spectrometric analysis, mainly mass spectrometry and NMR and comparison of these data described in the literature.

【 授权许可】

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