Phytochemical study of the wood from Guarea macrophylla (Meliaceae)

Química Nova

Universidade Federal da Bahia, Salvador, Brasil¹  Roque, Nídia F.¹  Lago, João Henrique G.¹  Universidade Federal de São Paulo, Diadema, Brasil¹ 

关键词: Meliaceae;    Guarea macrophylla;    cycloartane triterpenoids.;   

DOI  :  10.1590/S0100-40422009000900022

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

In the present work, the crude ethanol extract from wood of G. macrophylla was submitted to liquid/liquid partition between hexane, CH2Cl2, EtOAc and n-BuOH. Each phase was individually chromatographed over silica gel, Sephadex LH-20 or Amberlite XAD-2 to give eight terpene derivatives, such as five sesquiterpenoids (caryophyllene oxide, guai-6-en-10β-ol, spathulenol, aromadendrane-4β,10α-diol and aloaromadendrane-4α,10β-diol) as well as three triterpenoids (cicloart-24-ene-3β,23(R*)-diol, cicloart-24-ene-3β,23(S*)-diol, and cicloart-23E-ene-3β,25-diol). Additionally, were isolated three fatty acids (linolenic, linoleic and stearic), two steroids (sitosterol and stigmasterol) and sacarose. The structures of all these compounds were characterized by spectrometric analysis, mainly mass spectrometry and NMR and comparison of these data described in the literature.

【 授权许可】

Unknown