Genetic diversity of noroviruses in Brazil

Memórias do Instituto Oswaldo Cruz

Julia Monassa Fioretti¹  Mônica Simões Rocha Ferreira¹  Matias Victoria¹  Carmen Baur Vieira¹  Maria Da Penha Trindade Pinheiro Xavier¹  José Paulo Gagliardi Leite¹  Marize Pereira Miagostovich¹ 

[1] ,Instituto Oswaldo Cruz-Fiocruz Laboratório de Virologia Comparada e Ambiental Rio de Janeiro RJ ,Brasil

关键词: norovirus;    genotypes;    gastroenteritis;    Brazil;   

DOI  :  10.1590/S0074-02762011000800008

来源: SciELO

【 摘 要 】

Norovirus (NoV) infections are a major cause of acute gastroenteritis outbreaks around the world. In Brazil, the surveillance system for acute diarrhoea does not include the diagnosis of NoV, precluding the ability to assess its impact on public health. The present study assessed the circulation of NoV genotypes in different Brazilian states by partial nucleotide sequencing analysis of the genomic region coding for the major capsid viral protein. NoV genogroup II genotype 4 (GII.4) was the prevalent (78%) followed by GII.6, GII.7, GII.12, GII.16 and GII.17, demonstrating the great diversity of NoV genotypes circulating in Brazil. Thus, this paper highlights the importance of a virological surveillance system to detect and characterize emerging strains of NoV and their spreading potential.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License