Memórias do Instituto Oswaldo Cruz | |
Polygodial, the fungitoxic component from the Brazilian medicinal plant Polygonum punctatum | |
Tânia Maria De Almeida Alves1  Fabiane Lacerda Ribeiro1  Helmut Kloos1  Carlos Leomar Zani1  | |
[1] ,Fundação do Instituto Oswaldo Cruz Centro de Pesquisas René Rachou Laboratório de Química de Produtos NaturaisBelo Horizonte MG ,Brasil | |
关键词: medicinal plants; Cladosporium sphaerospermum; antifungal; polygodial; sesquiterpene; Brazil; | |
DOI : 10.1590/S0074-02762001000600016 | |
来源: SciELO | |
【 摘 要 】
Polygonum punctatum (Polygonaceae) is an herb known in some regions of Brazil as "erva-de-bicho" and is used to treat intestinal disorders. The dichloromethane extract of the aerial parts of this plant showed strong activity in a bioautographic assay with the fungus Cladosporium sphaerospermum. The bioassay-guided chemical fractionation of this extract afforded the sesquiterpene dialdehyde polygodial as the active constituent. The presence of this compound with antibiotic, anti-inflammatory and anti-hyperalgesic properties in "erva-de-bicho" may account for the effects attributed by folk medicine to this plant species.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202103040046017ZK.pdf | 47KB | download |