Memórias do Instituto Oswaldo Cruz | |
Morphometry of submucous and myenteric esophagic plexus of dogs experimentally reinfected with Trypanosoma cruzi | |
Evandro Mm Machado2  Deolino J Camilo Júnior1  Simone W Pinheiro1  Edison Reis Lopes1  Alexandre J Fernandes2  João Carlos Pinto Dias2  Sheila J Adad1  | |
[1] ,Fiocruz Centro de Pesquisas René Rachou Belo Horizonte MG ,Brasil | |
关键词: Chagas disease; Trypanosoma cruzi; dog; reinfection; esophagus; myenteric plexus; | |
DOI : 10.1590/S0074-02762001000400017 | |
来源: SciELO | |
【 摘 要 】
We carried out a morphometric study of the esophagus of cross-bred dogs experimentally infected or consecutively reinfected with Trypanosoma cruzi 147 and SC-1 strains, in order to verify denervation and/or neuronal hypertrophy in the intramural plexus. The animals were sacrificed in the chronic stage, 38 months after the initial infection. Neither nests of amastigotes, nor myositis or ganglionitis, were observed in all third inferior portions of esophageal rings analyzed. No nerve cell was identified in the submucous of this organ. There was no significant difference (p>0.05) between the number, maximum diameter, perimeter, or area and volume of the nerve cells of the myenteric plexus of infected and/or reinfected dogs and of the non-infected ones. In view of these results we may conclude that the 147 and SC-1 strains have little neurotropism and do not determine denervation and/or hypertrophy in the intramural esophageal plexuses in the animals studied, independent of the reinfections.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202103040045966ZK.pdf | 75KB | download |