Human leptospirosis in a slum area in the city of Rio de Janeiro, Brazil: a serological and epidemiological study

Memórias do Instituto Oswaldo Cruz

M. M. Pereira¹  J. Andrade¹ 

[1] ,Instituto Oswaldo Cruz Departamento de Bacteriologia Rio de Janeiro,Brasil

关键词: human leptospirosis;    serology;    epidemiology;   

DOI  :  10.1590/S0074-02761990000100007

来源: SciELO

【 摘 要 】

A serologic survey was carried out on slum dwellers in the city of Rio de Janeiro. A total of 259 serum samples from male and female individuals of different age groups were tested for the presence of antileptospire antibodies by microagglutination. Prevalence data were analyzed in relation to the major risk factors present at the site, mainly represented by the presence of carrier animals and the occurence of frequent floods. Of the samples tested, 25% reacted with antigens of different serogroups at titres ranging from 1:100 to 1:6400, with a predominance of titres <= 1:400; 35% of positive sera reacted with leptospirae of the Icterohaemorrhagiae serogroup. Reactions with Djasiman, Panama, Javanica, Canicola, Pyrogenes, Australis, Ballum, Sejroe, Bataviae, Grippotyphosa, Autumnalis and Cynopteri were also detected, though at lower frequencies. There was no statistically significant difference between sexes, but higher prevalence rates were found to be associated with increasing age. A focus of infection was characterized, in which social and economic factors contribute to the persistance of leptospirae by favoring the proliferation of the main reservoir.

【 授权许可】

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