Endocytosis-inducer adhesins produced by enteropathogenic serogroups of Escherichia coli participate on bacterial attachment to infant enterocytes

Memórias do Instituto Oswaldo Cruz

João Ramos Costa Andrade¹  Carla Cavalheiro Da Silva¹ 

[1] ,UERJ Faculdade de Ciências Médicas Serviço de Microbiologia e ImunologiaRio de Janeiro,Brasil

关键词: Escherichia coli;    infantile diarrhea;    bacterial adhesiveness;    bacterial pathogenicity;    Escherichia coli;    diarréia infantil;    aderência bacteriana;    patogenicidade bacteriana;   

DOI  :  10.1590/S0074-02761987000100015

来源: SciELO

【 摘 要 】

Enteropathogenic E. coli (EPEC) infection of Hep-2 cells preoceeds through bacterial attachment to cell surface and internalization of adhered bacteria. EPEC attachment is a prerequisite for cell infection and is mediated by adhesins that recognize carbohydrate-containing receptors on cell membrane. Such endocytosis-inducer adhesins (EIA) also promote EPEC binding to infant enterocytes, suggesting that EIA may have an important role on EPEC gastroenteritis.

【 授权许可】

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