Nasal secretions of Neisseria lactamica carriers have an inhibitory effect on Neisseria meningitidis attachment to human oroepithelial cells

Memórias do Instituto Oswaldo Cruz

João Ramos Costa Andrade²  Margareth Da Cunha Marques²  Milden Rodrigues De Santa Rosa¹ 

[1] ,UERJ Faculdade de Ciências Médicas Serviço de Microbiologia e ImunologiaRio de Janeiro,Brasil

关键词: Neisseria meningitidis;    Neisseria lactamica;    carrier state;    bacterial adhesiveness;   

DOI  :  10.1590/S0074-02761986000400013

来源: SciELO

【 摘 要 】

Nasal secretions of volunteers colonized by N. lactamica impaired the attachment of N. lactamica and of meningococci of groups A and B to oroepithelial cells. Bacterial adherence was found to be mediated by nonpiliated adhesins with antigen(s) which probably are shared by the strains tested. Although a strong attachment-inhibiting activity arises in their nasal secretions, volunteers remained colonized by N. lactamica. This evidence suggest that the eradication of Neisseria carriage is a multifactorial event.

【 授权许可】

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