Parotid enlargement due to adenovirus infection in patient with human immunodeficiency virus infection

Revista da Sociedade Brasileira de Medicina Tropical

Maria Irma Seixas Duarte¹  Valdir Sabbaga Amato¹  Juliane Gomes De Paula¹  David Everson Uip¹  Marcos Boulos¹  Vicente Amato Neto¹ 

关键词: Human immunodeficiency virus;    Adenovirus;    Parotid gland;    Vírus da imunodeficiência humana;    Adenovirus;    Parótida;   

DOI  :  10.1590/S0037-86821996000500015

来源: SciELO

【 摘 要 】

The authors report a case of adenovirus- induced enlargement of the parotid gland involving a patient infected with human immunodeficiency virus (HIV). Physical examination revealed good general condition, no fever and bilateral enlargement of the parotid region, which was of increased consistency and slightly tender to palpation. Histological examination of the parotid gland demonstrated a slight periductal lymphomononuclear inflammatory infiltrate with the presence of focal points of necrosis. Tests to determine the presence of fungi and alcohol-acid resistent bacilli were negative. Immunohistochemistry for cytomegalovirus, heipes simplex, HIV p24 antigen and adenovirus showed positivity only for adenovirus in the epithelial nuclei of numerous gland ducts. Tins is the third case of this type reported in the literature, indicating the importance of including adenovirus in the differential diagnosis of this condition.

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