Correlation between the neutrophil-lymphocyte count ratio and bacterial infection in patient with human immunodeficiency virus

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Kusnadi, D.^1 ; Liwang, M.N.I.^2 ; Katu, S.^2 ; Mubin, A.H.^2 ; Halim, R.^2

Tropical Infection Medicine Division, Medical Faculty of Hasanuddin University, Makassar, Indonesia^1

Internal Medicine Department, Medical Faculty of Hasanuddin University, Makassar, Indonesia^2

关键词: Additional sampling;    Antibiotic therapy;    Bacterial infections;    HIV patients;    Human immunodeficiency virus;    Procalcitonin;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012029/pdf
DOI  :  10.1088/1755-1315/125/1/012029

来源: IOP

【 摘 要 】

Parameters for starting antibiotic therapy such as CRP andleukocytosis are considered non-specific. Previous studies have shown the Neutrophil-Lymphocyte Count Ratio (NLCR) can serve as the basis of bacterial infection, the level of infection, and the basis of antibiotic therapy. Compared with the Procalcitonin parameter, this NLCR is rapid, an inexpensive and requires no additional sampling. To determine the correlation between The Neutrophil-LymphocyteCount Ratio to bacterial infection in HIV patients. This study was a cross-sectional observational approach to HIV subject at Wahidin Sudirohusodo and Hasanuddin University Hospital. The subjects performed routine blood, microbiology test,and blood Procalcitonin levels tests. Then performed NLCR calculations based on routine blood results. The subjects then grouped the presence or absence of bacterial infection.In 146 study subjects, there were 78 (53.4%) with bacterial infections and 68 (46.6%) without bacterial infection as controls. Subjects with bacterial infections had higher total neutrophils (84.83) compared with non-bacterial infections. Subjects with bacterial infections had total lymphocytes with an average of 8.51 lower than non-bacterial infections. Subjects with bacterial infections had higher NLCR values with an average of 12.80. The Neutrophil-Lymphocyte Count Ratio can become a marker of bacterial infection in HIV patients.