A clinico-pathological study of 163 untreated cases of chronic hepatitis C

Revista da Sociedade Brasileira de Medicina Tropical

Joachim Graf¹  Kan Toriyama¹  Hideyo Itakura¹ 

[1] ,Nagasaki University Institute of Tropical Medicine Department of PathologyNagasaki,Japan

关键词: Chronic hepatitis C;    Bile duct damage Lymphoid aggregate;    Histopathology;    Hepatite crônica C;    Lesão de dueto biliar;    Agregado linfóide;    Histopatologia;   

DOI  :  10.1590/S0037-86821996000100005

来源: SciELO

【 摘 要 】

We performed a clinico-pathological study of 163 untreated cases of chronic hepatitis C. Eighty five percent of the patients were clinically asymptomatic and their physical examinations sbowed unremarkable or minimal changes at the time of the liver biopsy Liver function tests tended to present slight abnormalities, involving mild elevations of the activity of the aminotransferases and gamma-glutamil transferase levels. In spite of these mild abnormalities advanced chronic liver disease ivas histologically detected in eighty nine percent of the patients, mainly showing chronic active hepatitis. The most characteristic histological finding ivas an interlobular bile duct damage which correlated with the presence of tymphoid aggregates in the portal tracts and with the development of fibrosis.

【 授权许可】

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