Treatment of pemphigus vulgaris and pemphigus foliaceus: experience with 71 patients over a 20 year period

Revista do Instituto de Medicina Tropical de São Paulo

Nurimar C. Fernandes²  Mauricio Perez¹ 

[1] ,Universidade Federal do Rio de Janeiro Faculdade de Medicina Departamento de Clínica Médica RJ ,Brasil

关键词: Pemphigus vulgaris;    Pemphigus foliaceus;    Treatment;   

DOI  :  10.1590/S0036-46652001000100007

来源: SciELO

【 摘 要 】

Forty one cases of pemphigus vulgaris and thirty cases of pemphigus foliaceus were investigated at Hospital Universitário Clementino Fraga Filho from 1978 to 1999. They were divided into two treatment groups: one group received up to 100 mg of oral prednisone daily and the other group received >120 mg daily. The dose up to 100 mg provided good initial control of pemphigus vulgaris and pemphigus foliaceus and did not increase the mortality rate associated to disease. The dose >120 mg induced higher morbidity. These data allowed us to establish a regimen of oral prednisone (1-2 mg/kg/daily) with maximum of 120 mg daily in the treatment of pemphigus vulgaris and pemphigus foliaceus.

【 授权许可】

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