Estudo do comportamento dos linfócitos derivados do timo em pacientes com pênfigo foliáceo na presença de levamisol

Revista da Sociedade Brasileira de Medicina Tropical

Universidade Federal de Minas Gerais¹  Acedo, Maria Dolores Porto¹  Antunes, Lucyr Jones¹ 

关键词: Pemphigus foliaceus;    Lymphocytes;    Corticosteroid;    Levamisole;   

DOI  :  10.1590/S0037-86821984000100006

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

T lymphocytes from patients with Pemphigus foliaceus were studied fortheir ability to form E rosettes in thepresence of different concentrations of the immunostimulant levamisole. Lymphocytes from patients before systemic corticotherapy did not show stimulation when incubated with levamisole. Lymphocytes from patients submitted to corticotherapy had their ability to form rosettes inhibited. Those data suggest that the lymphocytes from patients with Pemphigus foliaceus may have some kind of defect in the phosphodiesterase of cyclic AMP.

【 授权许可】

Unknown