期刊论文详细信息
Revista do Instituto de Medicina Tropical de São Paulo | |
Chronic gastritis and Helicobacter pylori in digestive form of Chagas' disease | |
A. J. A. Barbosa1  D. M. M. Queiroz1  A. M. M. F. Nogueira1  M. J. A. Roquette Reis1  E. N. Mendes1  G. A. Rocha1  L. M. F. Romanello1  L. E. A. Troncon1  | |
[1],Faculdade de Medicina de Ribeirão Preto Departamento de Clínica Médica Ribeirão Preto SP ,Brasil | |
关键词: Chagas' disease; Megaesophagus; Megacolon; Chronic gastritis; H. pylori; | |
DOI : 10.1590/S0036-46651993000200002 | |
来源: SciELO | |
【 摘 要 】
Patients with the digestive form of Chagas'disease frequently present chronic gastritis. As the microorganism Helicobacter pylori is now accepted as the most common cause of human chronic gastritis, the present work was undertaken to verify a possible relationship between the presence of this bacterium and inflammatory changes of antral mucosa in chagasic patients. Seventeen chagasics, with megaesophagus and or megacolon were studied. Fragments from two different regions of antral mucosa were obtained by endoscopy, fixed in 4% neutral formaldehyde and embedded in paraffin. The sections were stained by haematoxylin and eosin for histology analysis, and by carbolfuchsin for H. pylori identification. H. pylori was found in 16 (94.1%) chagasic patients, all of them presenting chronic gastritis. Superficial gastritis was seen in 9 (52.9%) while atrophic gastritis was present in 8 (47.1%) patients. H. pylori was present on gastric mucosa of 8 (100%) patients with atrophic gastritis and of 8 (88.8%) patients with superficial gastritis. We concluded that the microorganism H. pylori should be considered a possible factor connected with the etiopathogenesis of chronic superficial and atrophic gastritis frequently observed in patients with the digestive form of Chagas' disease.【 授权许可】
CC BY-NC
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