Severe digestive pathology associated with chronic Chaga's disease in Ecuador: report of two cases

Revista da Sociedade Brasileira de Medicina Tropical

Angel G. Guevara¹  José W. Eras²  Marcelo Recalde²  Luis Vinueza²  Philip J. Cooper²  Ali Ouaissi²  Ronald H. Guderian² 

[1] ,Hospital Vozandes-QuitoQuito,Ecuador

关键词: Chagas' disease;    T. cruzi;    PCR;    Megaesophagus;    Megacolon;    Ecuador;    Doença de Chagas;    T. cruzi;    PCR;    Megaesôfago;    Megacólon;    Ecuador;   

DOI  :  10.1590/S0037-86821997000500007

来源: SciELO

【 摘 要 】

DNA extracted from peripheral blood of two Ecuadorian patients showing severe digestive pathology was amplified by the polymerase chain reaction using a Trypanosoma cruzi specific oligonucleotide primers derived from the primary sequence of a cDNA encoding for a 24 kDa excretory/secretory protein. The positive PCR results together with the clinical findings confirmed that both patients had a digestive pathology due to Chagas' disease. This pathology could be more frequent than previously described in the chagasic endemic regions of Andean countries.

【 授权许可】

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