Towards a unified theory of health-disease: II. Holopathogenesis

Revista de Saúde Pública

Naomar Almeida Filho¹ 

关键词: Health;    Disease;    Health-Disease Process;    Comprehensive Health Care;    Holistic Health;    Saúde;    Doença;    Processo Saúde-Doença;    Assistência Integral à Saúde;    Saúde Holística;   

DOI  :  10.1590/S0034-8910.2014048005196

来源: SciELO

【 摘 要 】

This article presents a systematic framework for modeling several classes of illness-sickness-disease named as Holopathogenesis. Holopathogenesis is defined as processes of over-determination of diseases and related conditions taken as a whole, comprising selected facets of the complex object Health. First, a conceptual background of Holopathogenesis is presented as a series of significant interfaces (biomolecular-immunological, physiopathological-clinical, epidemiological-ecosocial). Second, propositions derived from Holopathogenesis are introduced in order to allow drawing the disease-illness-sickness complex as a hierarchical network of networks. Third, a formalization of intra- and inter-level correspondences, over-determination processes, effects and links of Holopathogenesis models is proposed. Finally, the Holopathogenesis frame is evaluated as a comprehensive theoretical pathology taken as a preliminary step towards a unified theory of health-disease.

【 授权许可】

CC BY   
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