Arquivos de Neuro-Psiquiatria | |
Alzheimer's 100th anniversary of death and his contribution to a better understanding of Senile dementia | |
Eliasz Engelhardt1  Marleide Da Mota Gomes1  | |
关键词: dementia; Senile dementia; hystory of medicine; Alzheimer; Alzheimer’ disease; demência; Demência senil; história da medicina; Alzheimer; doença de Alzheimer; | |
DOI : 10.1590/0004-282X20140207 | |
来源: SciELO | |
【 摘 要 】
Initially the trajectory of the historical forerunners and conceptions of senile dementia are briefly presented, being highlighted the name of Alois Alzheimer who provided clinical and neuropathological indicators to differentiate a group of patients with Senile dementia. Alzheimer's examination of Auguste D’s case, studied by him with Bielschowsky’s silver impregnation technique, permitted to identify a pathological marker, the intraneuronal neurofibrillary tangles, characterizing a new disease later named after him by Kraepelin – Alzheimer’s disease. Over the time this disorder became one of the most important degenerative dementing disease, reaching nowadays a status that may be considered as epidemic.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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RO202103040011873ZK.pdf | 206KB | download |