Alzheimer's 100th anniversary of death and his contribution to a better understanding of Senile dementia

Arquivos de Neuro-Psiquiatria

Eliasz Engelhardt¹  Marleide Da Mota Gomes¹ 

关键词: dementia;    Senile dementia;    hystory of medicine;    Alzheimer;    Alzheimer’ disease;    demência;    Demência senil;    história da medicina;    Alzheimer;    doença de Alzheimer;   

DOI  :  10.1590/0004-282X20140207

来源: SciELO

【 摘 要 】

Initially the trajectory of the historical forerunners and conceptions of senile dementia are briefly presented, being highlighted the name of Alois Alzheimer who provided clinical and neuropathological indicators to differentiate a group of patients with Senile dementia. Alzheimer's examination of Auguste D’s case, studied by him with Bielschowsky’s silver impregnation technique, permitted to identify a pathological marker, the intraneuronal neurofibrillary tangles, characterizing a new disease later named after him by Kraepelin – Alzheimer’s disease. Over the time this disorder became one of the most important degenerative dementing disease, reaching nowadays a status that may be considered as epidemic.

【 授权许可】

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