Arquivos de Neuro-Psiquiatria | |
Urinary dysfunction with detrusor hyperactivity in women with Parkinson's disease cannot be blamed as a factor of worsening motor performance | |
Raimundo Nonato Campos-sousa1  Elizabeth Maria Aparecida Barasnevicius Quagliato1  Kelson James Almeida1  Inacio Augusto Dias De Castro1  Viriato Campelo1  | |
关键词: detrusor overactivity; detrusor hyperreflexia; Parkinson's disease; urinary symptoms; hiperatividade detrusora; hiperreflexia detrusora; doenca de Parkinson; sintomas urinarios; | |
DOI : 10.1590/0004-282X20130101 | |
来源: SciELO | |
【 摘 要 】
Introduction Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature. Methods A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated. Results Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups. Conclusion Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.
【 授权许可】
CC BY
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