Arquivos de Neuro-Psiquiatria | |
Hippocampal volume and CDR-SB can predict conversion to dementia in MCI patients | |
João Guilherme Fiorani Borgio2  Leonardo Baldaçara1  Walter Dos Santos Moraes2  Acioly L. T. Lacerda1  Maria Beatriz Montaño1  Andrea Parolin Jackowski1  Sérgio Tufik2  Luiz Roberto Ramos1  Rodrigo Affonseca Bressan1  | |
[1] ,Universidade Federal de São Paulo (UNIFESP) Department of Psychobiology São Paulo SP ,Brazil | |
关键词: geriatric psychiatry; neuroimage; mild cognitive impairment; psiquiatria geriátrica; neuroimagem; distúrbio cognitivo leve; | |
DOI : 10.1590/S0004-282X2012001100003 | |
来源: SciELO | |
【 摘 要 】
OBJECTIVE: To evaluate the combination of two factors: clinical dementia rating sum of boxes scores (CDR-SB) and hippocampal volume (HV) as predictors of conversion from mild cognitive impairment (MCI) to dementia. METHODS: Twenty-eight individuals (9 normal and 19 with MCI) were classified according to their CDR sum of boxes scores into 3 groups. RESULTS: The hippocampal volume was significantly lower in the high-risk group and in those who developed dementia after two years. The rate of conversion was crescent among the three groups. CONCLUSION: We were proposed an additional measurement of the hippocampal volume which may be helpful in the prognosis. However, we noted that the CDR-SB is a method as efficient as neuroimaging to predict dementia with the advantage of being a procedure for low cost and easy implementation, more consistent with public policy.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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