Seasonal distribution and evolving forms of multiple sclerosis patients diagnosed from April 2004 to November 2007

Arquivos de Neuro-Psiquiatria

Hermes Fundora-hernández¹  Alberto J. Dorta-contreras¹  Maray Socias-lópez¹  Silvana Fraga-santana¹  Silvia Nicté Villatoro-rodríguez¹  Bárbara Padilla-docal¹  Elena Noris-garcía¹  Raisa Bu-coifiu-fanego¹  Marlén González-hernández¹ 

[1] ,Facultad de Ciencias Médicas Instituto Superior de Ciencias Médicas de La Habana Laboratorio Central de Líquido Cefalorraquídeo

关键词: multiple sclerosis;    epidemiology;    environmental factors;    esclerosis múltiple;    epidemiología;    factores ambientales;   

DOI  :  10.1590/S0004-282X2009000400016

来源: SciELO

【 摘 要 】

BACKGROUND: Multiple sclerosis (MS) was first reported in Cuba in 1965. The most frequent appearance is observed in the first six months of the year. OBJECTIVE: To determine the seasonal distribution and evolving forms of MS patients diagnosed with the disease between April 2004 and November 2007. METHOD: Twenty-one patients with suspected MS and 42 outbreaks were studied. Patients were classified according to Lublin and Revingold's criteria for clinical forms and according to McDonald. RESULTS: Most patients were classified in outbreak and remission and only two patients classified as primary-progressive multiple sclerosis. The higher number of outbreaks occurred in the first two quarters of the year. CONCLUSION: It is recommended to study further weather variables that may be related to the emergence of these outbreaks in our environment.

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