Effect of protein and vitamin B deficiency on the morpho-quantitative aspects of the myenteric plexus of the descending colon of adult rats

Arquivos de Neuro-Psiquiatria

Eduardo José De Almeida Araújo¹  Débora De Mello Gonçales Sant'ana¹  Sônia Lucy Molinari¹  Marcílio Hubner De Miranda Neto¹ 

[1] ,Universidade ParanaenseUmuarama PR ,Brasil

关键词: enteric neurons;    protein malnutrition;    descending colon;    vitamin B;    myenteric plexus;    neurônios entéricos;    desnutrição protéica;    colo descendente;    vitamina B;    plexo mioentérico;   

DOI  :  10.1590/S0004-282X2003000200012

来源: SciELO

【 摘 要 】

We carried out this work with the purpose of studying the effects of protein and vitamin B deficiency on the morphologic and quantitative aspects of the myenteric plexus of the descending colon of adult Rattus norvegicus. Twenty-eight rats were divided in two groups, one of them receiving chow with 22% protein level (control) and the other fed with chow having 8% protein level without vitamin B supplementation, during 120 days. Whole-mounts of the descending colon were prepared and stained with Giemsa, NADH-diaphorase and NADPH-diaphorase. The undernourished rats had a body weight 11.84% less than the control group. Relative to the controls, the experimental group had a colonic area 48% smaller, 51.9% less Giemsa-stained neurons, 28.3% less NADH-diaphorase positive neurons and 24.2% less NADPH-diaphorase positive neurons.

【 授权许可】

CC BY   
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