Organophosphate-induced delayed neuropathy: case report

Arquivos de Neuro-Psiquiatria

Luiz Felipe R Vasconcellos²  Ana Cláudia Leite¹  Osvaldo J M Nascimento² 

[1] ,Federal University of Rio de Janeiro Institute of Neurology Deolindo Couto Rio de Janeiro RJ ,Brasil

关键词: neuropathy;    polyneuropathy;    organophosphate;    neuropatia;    polineuropatia;    organofosforados;   

DOI  :  10.1590/S0004-282X2002000600022

来源: SciELO

【 摘 要 】

Organophosphate induced delayed neuropathy (OPIDN) is an uncommon clinical condition. It occurs in association with the ingestion of great amounts of organophosphate after the stimulation of cholinergic receptor. The clinical picture is characterized by a distal paresis in lower limbs associated with sensitive symptoms. Electrodiagnostic studies show a motor axonal neuropathy. Involvement of the central nervous system may occur. We describe a 39 years-old female patient who developed hyperesthesia associated with lower limbs paresis, fourteen days after she had ingested a Dichlorvos-based insecticide. Electrophysiological study was characterized by an axonal polyneuropathy pattern. Pyramidal tract dysfunction was observed later in upper limbs. Considering that both peripheral and central nervous systems are involved we believe that the more appropriated term would be organophosphate induced delayed neuropathy (OPIDN) instead of organophosphate induced delayed polyneuropathy (OPIDP).

【 授权许可】

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