Chronic inflammatory demyelinating polyradiculoneuropathy in chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: case report

Arquivos de Neuro-Psiquiatria

Paulo José Lorenzoni¹  Rosana Herminia Scola¹  Ana Lucila Moreira Carsten¹  Ana Paula Trentin¹  Hélio A.g. Teive¹  Ricardo Pasquini¹  Lineu C. Werneck¹ 

[1] ,Federal University of Paraná Hospital de Clínicas Internal Medicine DepartmentCuritiba PR ,Brazil

关键词: graft-versus-host disease;    hematopoietic stem cell transplant;    bone marrow transplantation;    neuropathy;    polyneuropathy;    doença do enxerto contra o hospedeiro;    transplante de células hematopoiéticas;    transplante de medula óssea;    neuropatia;    polineuropatia;   

DOI  :  10.1590/S0004-282X2007000400031

来源: SciELO

【 摘 要 】

The chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an unusual but important complication of hematopoietic stem cell transplantation (HSCT) rarely reported to date. We describe a 17-year-old woman with a diagnosis of acute myeloid leukemia due to Fanconi's anemia who was submitted to allogeneic HSCT and developed CIDP as part of graft-versus-host disease. Investigation showed high cerebrospinal fluid protein; electrophysiological studies revealed sensory-motor demyelinating polyradiculoneuropathy; muscle and nerve biopsy were compatible with CIDP.

【 授权许可】

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