Late onset temporal lobe epilepsy with MRI evidence of mesial temporal sclerosis following acute neurocysticercosis: case report

Arquivos de Neuro-Psiquiatria

Eliane Kobayashi¹  Carlos A.m. Guerreiro¹  Fernando Cendes¹ 

[1] ,Universidade Estadual de Campinas Faculdade de Ciências Médicas Departamento de NeurologiaCampinas SP ,Brazil

关键词: temporal lobe epilepsy;    hippocampal atrophy;    mesial temporal sclerosis;    acute neurocysticercosis;    epilepsia de lobo temporal;    atrofia hipocampal;    esclerose mesial temporal;    neurocisticercose aguda;   

DOI  :  10.1590/S0004-282X2001000200021

来源: SciELO

【 摘 要 】

The objective of this case report is to describe magnetic resonance imaging (MRI) evidence of mesial temporal sclerosis (MTS) in a patient with new onset temporal lobe epilepsy (TLE) and acute neurocysticercosis with multiple cysts. A 56 years old man with new onset headache, Simple Partial Seizures and Complex Partial Seizures underwent CT scan and lumbar puncture as diagnose proceeding. Multiple cysts and meningitis were identified, with a positive immunology for cysticercosis. Seizures were recorded over the left temporal region in a routine EEG. Treatment with albendazole was performed for 21 days, with clinical improvement and seizure remission after 4 months. An MRI scan 11 months after treatment, showed complete resolution of those cystic lesions and a left hippocampal atrophy (HA) with hyperintense T2 signal. The presence of HA and hyperintense T2 signal in this patient has not, to date, been associated with a poor seizure control. CONCLUSIONS: This patient presented with MRI evidence of left MTS after new onset partial seizures of left temporal lobe origin. Although we did not have a previous MRI scan, it is likely that this hippocampal abnormality was due to the acute inflammatory response to cysticercosis associated to repeated partial seizures. This suggests that acute neurocysticercosis associated with repeated seizures may cause MTS and late onset TLE.

【 授权许可】

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