Sacrococcygeal chordoma in a 9-year-old boy

Arquivos de Neuro-Psiquiatria

Lúcia De Noronha¹  Betina Werner¹  Carmem Maria C. Mendonça²  Luiz Nomura¹  Luiz Fernando Bleggi-torres¹ 

[1] ,University of Paraná Hospital de Clínicas Department of Pediatrics

关键词: chordoma;    immunohistochemistry;    notochord;    bone tumors;    cordoma;    imuno-histoquímica;    notocorda;    tumores ósseos;   

DOI  :  10.1590/S0004-282X1995000400018

来源: SciELO

【 摘 要 】

A case of sacrococcygeal chordoma in a 9-year-old boy is presented. The symptoms at presentation were pain in both legs and sacrococcygeal region for the last two years that increased in the last four weeks irradiating mainly to the left leg. X-ray and CT scan examinations of the lumbar region revealed an expansive process in the coccygeal region with multiple calcifications and a partially eroded coccyx. There was no invasion of the retroperitoneum and regional lymph nodes. A biopsy was performed and showed cords and nests of cells with large cytoplasm, sometimes vacuolated, nuclei with moderate pleomorphism and clumped chromatin. Immunohistochemistry with avidin-biotin peroxidase technique showed positivity for CK, S-100 protein, CEA, vimentin and to EMA. Chordomas are a distinctly uncommon neoplasm in the first two decades of life, specially in the sacrococcygeal region. They have an aggressive behavior. Treatment of choice is complete resection.

【 授权许可】

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