Endothelial keratoplasty: evolution and horizons

Arquivos Brasileiros de Oftalmologia

Gustavo Teixeira Grottone¹  Nicolas Cesário Pereira¹  José Álvaro Pereira Gomes¹ 

[1] ,Universidade Federal de São Paulo - UNIFESP Ophthalmology Department Cornea SectionSão Paulo SP ,Brazil

关键词: Endothelium;    corneal;    Corneal transplantation;    Descemet stripping endothelial keratoplasty;    Keratoplasty;    penetrating;    Translational medical research;    Cell transplantation;    Epitélio posterior;    Transplante de córnea;    Ceratoplastia endotelial com remoção da membrana de Descemet;    Ceratoplastia penetranting;    Pesquisa médica translacional;    Transplante de células;   

DOI  :  10.1590/S0004-27492012000600016

来源: SciELO

【 摘 要 】

Endothelial keratoplasty has been adopted by corneal surgeons worldwide as an alternative to penetrating keratoplasty (PK) in the treatment of corneal endothelial disorders. Since the first surgeries in 1998, different surgical techniques have been used to replace the diseased endothelium. Compared with penetrating keratoplasty, all these techniques may provide faster and better visual rehabilitation with minimal change in refractive power of the transplanted cornea, minimal induced astigmatism, elimination of suture-induced complications and late wound dehiscence, and a reduced demand for postoperative care. Translational research involving cell-based therapy is the next step in work on endothelial keratoplasty. The present review updates information on comparisons among different techniques and predicts the direction of future treatment.

【 授权许可】

CC BY   
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