Prevention of retinopathy of prematurity

Arquivos Brasileiros de Oftalmologia

João Borges Fortes Filho²  Gabriela Unchalo Eckert¹  Marcia Beatriz Tartarella¹  Renato Soibelmann Procianoy¹ 

[1] ,Universidade Federal do Rio Grande do Sul Faculdade de Medicina Department of Ophthalmology

关键词: Retinopathy of prematurity;    Blindness;    Risk factors;    Retinopatia da prematuridade;    Cegueira;    Fatores de risco;   

DOI  :  10.1590/S0004-27492011000300016

来源: SciELO

【 摘 要 】

Retinopathy of prematurity (ROP) is related to oxygen-regulated vascular endothelial growth factor and to insulin-like growth factor-I. After premature birth, supplemental oxygen induces a retinal hyperoxic condition with vasoconstriction and to a definitive interruption of retinal vasculogenesis. Peripheral ischemia may stimulate retinal neovascularization and the onset of additional ROP-related complications. The natural course of the disease may result in irreversible blindness if not promptly diagnosed and attended. Recently, a significant increase in the prevalence of ROP has been observed in survival rates of preterm infants, especially in emerging-economy countries in Latin America, Asia, and Eastern Europe. This article addresses the main preventive measures in ROP.

【 授权许可】

CC BY   
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